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Delta cell

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Overview

Delta cells (δ-cells or D cells) are somatostatin producing cells.

They can be found in the stomach, intestine and the Islets of Langerhans in the pancreas.

In rodents delta-cells are located in the periphery of the islets; in humans the islet architecture is generally less organized and delta-cells are frequently observed inside the islets as well.

In the electron microscope, delta-cells can be identified as cells with smaller and slightly more compact granules than beta cells.

Clinical significance

A tumor of the delta cells is called a “somatostatinoma“.

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