Delusional disorder MRI

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]

On MRI, delusional disorder is characterized by greater lateral ventricle volume and hyper intense MRI signals in deep white matter in temporal and frontal lobes.

• It is found that lateral ventricle volume in delusional disorder is much greater than that in schizophrenia and almost twice than that in healthy controls.
• Scientists have reported areas of hyper intense MRI signals in deep white matter in temporal and frontal lobes as an anatomically non-specific finding in late paraphrenia and later related these findings to localized disturbances of cerebral blood flow. Reduced cerebral blood flow in left parietal and temporal regions was also reported in a SPECT study.^[1]

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