Desmoid tumor classification

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sara Mohsin, M.D.[2]Faizan Sheraz, M.D. [3]

Overview

Based on the etiology, desmoid tumors may be classified as abdominal, intra-abdominal, extra-abdominal, multiple familial, associated with Gardner syndrome and associated with Turcot syndrome.

Classification	Features
Abdominal	Most commonly arise from anterior abdominal wall with 50% incidence
Extraabdominal	Desmoid tumors found in other body regions most often including: Shoulder girdle Upper arms Upper legs Hip/buttock region Trunk Head Neck Breast (history of breast cancer/breast surgery)
Intraabdominal	Arise from the tissue that connects the abdominal organs, involving: Mesentery Retroperitoneum Bowel Predominantly present in FAP patients
Multiple Familial	Hereditary predisposition
Gardner Syndrome Associated	Soft tissue tumors Osteoma
Turcot Syndrome Associated	Neural tumors

↑ Economou, Athanasios; Pitta, Xanthi; Andreadis, Efstathios; Papapavlou, Leonidas; Chrissidis, Thomas (2011). “Desmoid tumor of the abdominal wall: a case report”. Journal of Medical Case Reports. 5 (1): 326. doi:10.1186/1752-1947-5-326. ISSN 1752-1947.
↑ Colombo C, Foo WC, Whiting D, Young ED, Lusby K, Pollock RE; et al. (2012). “FAP-related desmoid tumors: a series of 44 patients evaluated in a cancer referral center”. Histol Histopathol. 27 (5): 641–9. doi:10.14670/HH-27.641. PMID 22419028.
↑ Neuman HB, Brogi E, Ebrahim A, Brennan MF, Van Zee KJ (2008). “Desmoid tumors (fibromatoses) of the breast: a 25-year experience”. Ann Surg Oncol. 15 (1): 274–80. doi:10.1245/s10434-007-9580-8. PMID 17896146.