Diabetic foot causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Anahita Deylamsalehi, M.D.[2]

Conditions such as peripheral neuropathy and ischemia are two common causes of diabetic foot ulcer formation. Decreased sensation due to peripheral neuropathy increase the risk of trauma which is another known cause of ulcer formation. Microorganisms such as staphylococcus aureus, pseudomonas aeruginosa, proteus mirabilis, escherichia coli and bacteroides fragilis are responsible for diabetic foot ulcer infection.

Common causes of diabetic foot may include:^[1][2][3][4]

• Peripheral neuropathy
• Ischemia from peripheral vascular disease
• Poor glycemic control
• In the presence of diabetic foot infection, the following are the most common causes of infections:
  • Staphylococcus aureus
  • Pseudomonas aeruginosa
  • Proteus mirabilis
  • Bacteroides fragilis
  • Escherichia coli (It was the most common gram negative bacteria based on one study. )
• Trauma and burn