Diabetic nephropathy history and symptoms

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dima Nimri, M.D. [2]

Overview

Patients with diabetic nephropathy can develop the manifestations of renal failure such as edema and unintentional weight gain late in the course of the disease.

History and Symptoms

Throughout its early course, diabetic nephropathy has no symptoms. They develop in late stages and may be a result of excretion of high amounts of protein in the urine or due to renal failure:^[1]

edema: swelling, usually around the eyes in the mornings; later, general body swelling may result, such as swelling of the legs
Foamy appearance or excessive frothing of the urine
Unintentional weight gain (from fluid accumulation)
Anorexia (poor appetite)
nausea and vomiting
malaise (general ill feeling)
Fatigue
headache
Frequent hiccups
Generalized itching

For full history and symptoms of chronic renal failure, click here
For full history and symptoms of diabetes mellitus, click here

References

↑ Webster AC, Nagler EV, Morton RL, Masson P (2016). “Chronic Kidney Disease”. Lancet. doi:10.1016/S0140-6736(16)32064-5. PMID 27887750.

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[pmid27887750-1] Webster AC, Nagler EV, Morton RL, Masson P (2016). “Chronic Kidney Disease”. Lancet. doi:10.1016/S0140-6736(16)32064-5. PMID 27887750.

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