Diatrizoic acid
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Diatrizoic acid (or its anionic form, Diatrizoate), also known as amidotrizoic acid, or 3,5-Diacetamido-2,4,6-triiodobenzoic acid, is an iodine-containing radiocontrast agent. It is also used to kill tapeworms.
Diatrizoate is considered a high-osmolality contrast agent. Its osmolality ranges from approximately 1500 mOsm/kg (50% solution)[1] to over 2000 mOsm/kg (76% solution).[2]
Administration
- It is given intravenously (under brand name Hypaque®, GE Healthcare) to enhance contrast in computed tomography, to image the kidneys and related structures, and to image blood vessels.
- It is given orally or by enema (Gastrografin®, Gastrovist®, Gastrovision®, MD-Gastroview®) to image the gastrointestinal tract.
- It is given by Foley catheter (Cystografin®) to image the urinary tract
Contraindications
A history of sensitivity to iodine is not a contraindication to using diatrizoate, although it suggests caution in use of the agent.
References
- ↑ Amersham Health (2006). “Hypaque sodium (Diatrizoate Sodium) injection, solution. Product label”. DailyMed. U.S. National Library of Medicine. Retrieved 2007-03-29. Unknown parameter
|month=ignored (help) - ↑ Amersham Health (2006). “Hypaque (Diatrizoate Meglumine and Diatrizoate Sodium) injection, solution. Product label”. DailyMed. U.S. National Library of Medicine. Retrieved 2007-03-29. Unknown parameter
|month=ignored (help)
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