Health Dictionary Find a Doctor

Diffuse esophageal spasm historical perspective

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor(s)-in-Chief: Madhu Sigdel M.B.B.S.[2]

Overview

DES was first described by Osgood, in 1889 in 6 patients presenting with chest pain and dysphagia. Development of high resolution esophageal manometry in 2000 has led to classification of esophageal motility disorders.

Historical Perspective

Discovery

  • In 1543: Vesalius, a Belgian anatomist was the first to describe the anatomy of the esophagus.
  • In 1674: T. Willis, an English physician used whale bone to dilate the esophagus.
  • In 1806: Philipp Bozzini, a German physician develops an early endoscope using a mirror and reflected light from a candle in an attempt to see the upper esophagus.
  • In 1843: Switzer, a Denmark physician invented esophageal dilators.
  • In 1844: John Watson, an American surgeon first performed esophagotomy for the relief of esophageal stricture.
  • In 1872: Christian Albert Theodor Billroth, an Austrian surgeon performed the first excision of the esophagus.
  • In 1883: H. Kronecker and S. Meltzer first used inserted balloons to describe esophageal motility and pressure measurements.
  • In 1954: L.R. Celestin first developed an esophageal tube for the treatment of malignant dysphagia.
  • DES was first described by Osgood, in 1889 in 6 patients presenting with chest pain and dysphagia.

Landmark Events in the Development of Treatment Strategies

  • In 2000, development of high resolution esophageal manometry has led to classification of esophageal motility disorders.

References

© 2026 MyEClinic – IFTM Institut für Telematik in der Medizin GmbH