Diffuse large B cell lymphoma biopsy

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2] Anila Hussain, MD [3]

Excisional Lymph node or extranodal tissue biopsy is diagnostic of diffuse large B cell lymphoma.

• Surgical Excision Biopsy of Lymph node or extranodal tissue is diagnostic of diffuse large B cell lymphoma.^[1]
• Needle-Core Excision and Endoscopic Biopsies should be reserved for patients in which surgery is too risky or impractical.
• FNA not used for diagnosis alone.
• To view findings on biopsy characteristic of each morphological variant of diffuse large B cell lymphoma, click here.
• morphological Diagnosis of DLBCL on Biopsy should always be confirmed by Immunophenotypic techniques like Flow cytometry or IHC or Both.

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