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Diffuse large B cell lymphoma causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]

Overview

There are no established causes for diffuse large B cell lymphoma.

Cause

The causes of diffuse large B-cell lymphoma are not well understood. Usually diffuse large B-cell lymphoma arises from normal B cells, but it can also represent a malignant transformation of other types of lymphoma or leukemia. Infection with Epstein-Barr virus has also been found to contribute to the development of some subgroups of diffuse large B cell lymphoma.

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