Dopamine agonist

Overview

A dopamine agonist is a compound that activates dopamine receptors, mimicking the effect of the neurotransmitter dopamine.

Uses

Some medical drugs act as dopamine agonists; they are typically used for treating Parkinson’s disease, and may be useful for restless legs syndrome (RLS). Both Requip (Ropinirole) and Mirapex (Pramipexole) are FDA approved for the treatment of RLS.

There is also an ongoing clinical trial to test the effectiveness of Requip (Ropinirole), a dopamine agonist, in reversing the symptoms of SSRI induced sexual dysfunction. ^[1]

Examples

Examples of dopamine agonists include:

Parlodel (bromocriptine)
Permax (Pergolide) – Removed from market March 29,2007.^[2]

Mirapex (Pramipexole)
Requip (Ropinirole)
Apokyn (apomorphine)

References

↑ Clinical trial number NCT00334048 at ClinicalTrials.gov – “Treating Sexual Dysfunction From SSRI Medication: a Study Comparing Requip CR to Placebo”
↑ http://www.fda.gov/bbs/topics/NEWS/2007/NEW01596.html

External links

Dopamine+Agonists at the US National Library of Medicine Medical Subject Headings (MeSH)

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[1] Clinical trial number NCT00334048 at ClinicalTrials.gov – “Treating Sexual Dysfunction From SSRI Medication: a Study Comparing Requip CR to Placebo”

[2] ttp://www.fda.gov/bbs/topics/NEWS/2007/NEW01596.html

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