Endocardial cushion defect medical therapy
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]
Overview
The management of endocardial cushion defect depends upon the type of defect, underlying etiology and associated cardiac conditions. Surgical correction of defective valve holds the the mainstay of treatment for endocardial cushion. Medical management provides supportive care in preparing the patient for surgery.
Medical Therapy
The management of endocardial cushion defect depends upon the type of defect, underlying etiology and associated cardiac conditions. Surgical correction of defective valve holds the the mainstay of treatment for endocardial cushion. The goal of medical management is to improve cardiac function as a prerequisite for surgery.
Medical management of endocardial cushion defect includes:[1][2]
| Medications | Mechanism of Action | Drugs |
|---|---|---|
| Diuretics | To reduce volume overload and pulmonary congestion |
|
| Inotropic agents | To improve myocardial contractility |
|
| ACE inhibitors |
|
|
Nutritional Support
- Caloric supplementation is often needed in patients with poor feeding and failure to thrive.
References
- ↑ Craig B (December 2006). “Atrioventricular septal defect: from fetus to adult”. Heart. 92 (12): 1879–85. doi:10.1136/hrt.2006.093344. PMC 1861295. PMID 17105897.
- ↑ Backer CL, Stewart RD, Mavroudis C (2007). “What is the best technique for repair of complete atrioventricular canal?”. Semin. Thorac. Cardiovasc. Surg. 19 (3): 249–57. doi:10.1053/j.semtcvs.2007.07.006. PMID 17983953.
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