| Endomyometritis Treatment
|
| Early Infection:1st 48 hours after delivery
|
▸ Cefoxitin 2 gm IV q6–8h
OR
▸ Ticarcillin-Clavulanate 3.1 gm IV q4–6h
OR
▸ DoripenemNAI 500 mg IV q8h
OR
▸ Imipenem 0.5 gm IV q6h
OR
▸ Meropenem 1 gm IV q8h
OR
▸ Ampicillin-Sulbactam 3 gm IV q6h
OR
▸ Ertapenem 1 gm IV q24h’
OR
▸ Pipracillin-Tazobactam 4.5 gm IV q6h (or 4-hr infusion of 3.375 gm q8h)
|
| PLUS
|
| ▸ Doxycycline 100 mg IV/po q12h
|
| OR
|
| ▸ Clindamycin 450–900 mg IV q8h
|
| PLUS
|
▸ Ceftriaxone 2 gm IV q24h
OR
▸ Gentamicin MDD: 2 mg per kg load, then 1.7 mg per kg q8h or OD: 5.1 (7 if critically ill) mg per kg q24h
|
| Late Infection:48 hours to 6 weeks after delivery
|
| ▸ Doxycycline 100 mg IV/po q12h x 14 days
|
