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Enprostil


Enprostil is a synthetic prostaglandin designed to resemble dinoprostone.

It is classified by the World Health Organization under “A02B: Drugs for peptic ulcer and gastro-oesophageal reflux disease.”

  • Toshina K, Hirata I, Maemura K, Sasaki S, Murano M, Nitta M, Yamauchi H, Nishikawa T, Hamamoto N, Katsu K (2000). “Enprostil, a prostaglandin-E(2) analogue, inhibits interleukin-8 production of human colonic epithelial cell lines”. Scand J Immunol. 52 (6): 570–5. PMID 11119262.
  • Tari A, Hamada M, Kamiyasu T, Sumii K, Haruma K, Inoue M, Kishimoto S, Kajiyama G, Walsh J (1997). “Effect of enprostil on omeprazole-induced hypergastrinemia and inhibition of gastric acid secretion in peptic ulcer patients”. Dig Dis Sci. 42 (8): 1741–6. PMID 9286243.
  • Ching C, Lam S (1995). “A comparison of two prostaglandin analogues (enprostil vs misoprostol) in the treatment of acute duodenal ulcer disease”. J Gastroenterol. 30 (5): 607–14. PMID 8574332.


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