Eosinophiluria
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Eosinophiluria is the presence of eosinophils in the urine either in the form of free eosinophils or eosinophils in casts. The use of Hansel’s stain for detecting urinary eosinophils has been associated with a higher sensitivity than using Wright’s stain.[1] The presence of any degree of eosinophiluria is considered to be pathologic[2] and has been noted in a wide variety of genitourinary diseases including acute interstitial nephritis, atheroembolic renal disease, rapidly progressive glomerulonephritis, chronic renal failure, IgA nephropathy, cystitis, prostatitis, pyelonephritis, postinfectious glomerulonephritis, obstructive nephropathy, urinary tract infection, and acute rejection of a renal allograft.[3][4][5][6][7]
Causes
Common Causes
- Acute interstitial nephritis
- Atheroembolic renal disease
- Rapidly progressive glomerulonephritis
- Urinary tract infection
Causes by Organ System
| Cardiovascular | Cholesterol embolism |
| Chemical/Poisoning | No underlying causes |
| Dental | No underlying causes |
| Dermatologic | No underlying causes |
| Drug Side Effect | Acute interstitial nephritis |
| Ear Nose Throat | No underlying causes |
| Endocrine | No underlying causes |
| Environmental | No underlying causes |
| Gastroenterologic | Ileal conduit surgery |
| Genetic | Interstitial cystitis |
| Hematologic | No underlying causes |
| Iatrogenic | Acute rejection of a renal allograft, Ileal conduit surgery |
| Infectious Disease | Cystitis, Postinfectious glomerulonephritis, Prostatitis, Pyelonephritis, Schistosoma haematobium, Urinary tract infection |
| Musculoskeletal/Orthopedic | No underlying causes |
| Neurologic | No underlying causes |
| Nutritional/Metabolic | No underlying causes |
| Obstetric/Gynecologic | No underlying causes |
| Oncologic | Bladder cancer |
| Ophthalmologic | No underlying causes |
| Overdose/Toxicity | No underlying causes |
| Psychiatric | No underlying causes |
| Pulmonary | No underlying causes |
| Renal/Electrolyte | Acute interstitial nephritis, Acute rejection of a renal allograft, Chronic renal failure, Churg-Strauss syndrome, IgA nephropathy, Obstructive nephropathy, Postinfectious glomerulonephritis, Pyelonephritis, Rapidly progressive glomerulonephritis |
| Rheumatology/Immunology/Allergy | Acute interstitial nephritis, Acute rejection of a renal allograft, Atheroembolic renal disease, Churg-Strauss syndrome, IgA nephropathy, Interstitial cystitis, Postinfectious glomerulonephritis |
| Sexual | No underlying causes |
| Trauma | No underlying causes |
| Urologic | Bladder cancer, Cystitis, Interstitial cystitis, Obstructive nephropathy, Prostatitis, Urinary tract infection |
| Miscellaneous | Interstitial cystitis |
Causes in Alphabetical Order
Reference
- ↑ Nolan CR, Anger MS, Kelleher SP (1986). “Eosinophiluria–a new method of detection and definition of the clinical spectrum”. The New England Journal of Medicine. 315 (24): 1516–9. doi:10.1056/NEJM198612113152404. PMID 2431314. Unknown parameter
|month=ignored (help) - ↑ Corwin HL, Haber MH (1987). “The clinical significance of eosinophiluria”. American Journal of Clinical Pathology. 88 (4): 520–2. PMID 2444100. Unknown parameter
|month=ignored (help) - ↑ Nolan CR, Kelleher SP (1988). “Eosinophiluria”. Clinics in Laboratory Medicine. 8 (3): 555–65. PMID 2458885. Unknown parameter
|month=ignored (help) - ↑ Sutton JM (1986). “Urinary eosinophils”. Archives of Internal Medicine. 146 (11): 2243–4. PMID 3535716. Unknown parameter
|month=ignored (help) - ↑ Corwin HL, Korbet SM, Schwartz MM (1985). “Clinical correlates of eosinophiluria”. Archives of Internal Medicine. 145 (6): 1097–9. PMID 4004436. Unknown parameter
|month=ignored (help) - ↑ Spencer ES, Petersen VP (1967). “The urinary sediment after renal transplantation. Quantitative changes as an index of the activity of the renal allograft reaction”. Acta Medica Scandinavica. 182 (1): 73–82. PMID 5339460. Unknown parameter
|month=ignored (help) - ↑ Kaye M, Gagnon RF (2008). “Acute allergic interstitial nephritis and eosinophiluria”. Kidney International. 73 (8): 980. doi:10.1038/sj.ki.5002777. PMID 18379530. Unknown parameter
|month=ignored (help)
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