Esthesioneuroblastoma physical examination

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]

Common physical examination findings of esthesioneuroblastoma include a reddish-gray, polypoid mass located in the upper nasal fossa, epistaxis, nasal discharge, nasal pain, facial swelling, trismus, proptosis, diplopia, anosmia, serous otitis media, cervical lymphadenopathy, retropharyngeal lymphadenopathy, decreased visual acuity, extraocular movement paralysis, altered mental status, and frontal headaches.

In majority of cases, malignancy is not considered until secondary symptoms such as deformity or cranial nerve impairment and facial pain are observed. A patient with a recurrent epistaxis and/or unilateral nasal obstruction lasting longer than 1-2 months should undergo a thorough nasal evaluation by an otolaryngologist.

• Reddish-gray, polypoid mass located in the upper nasal fossa
• Epistaxis
• Nasal discharge
• Nasal pain
• Facial pain
• Facial swelling
• Facial anesthesia
• Trismus
• Proptosis
• Diplopia
• Ear pain
• Serous otitis media
• Anosmia
• Hyposmia

• Cervical lymphadenopathy
• Retropharyngeal lymphadenopathy

• Decreased visual acuity
• Extraocular movement paralysis
• Frontal headaches
• Altered mental status

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