Extraglomerular mesangial cell

Extraglomerular mesangial cells (or lacis cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa.

Lacis cells form the juxtaglomerular apparatus in combination with two other types of cells: the macula densa of the thick ascending limb of Henle and Juxtaglomerular cells of the afferent arteriole. This apparatus controls blood pressure through the Renin-Angiotensin-Aldosterone system. The specific function of Lacis cells is not well understood. Although is it has been associated with the secretion of EPO. ^[1]

• mesangium
• intraglomerular mesangial cells

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