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FOLFIRI regimen

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aparna Vuppala, M.B.B.S. [2]

Synonyms and keywords:FOLFIRI; FOLFIRI Regimen; FOLFIRI regimen; Folinic Acid-Fluorouracil-Irinotecan Regimen

Overview

FOLFIRI regimen refers to a chemotherapy regimen consisting of leucovorin calcium (calcium folinate), 5-fluorouracil, and irinotecan used in the treatment of advanced-stage and metastatic colorectal cancer.[1][2]

Regimen

FOLLeucovorin calcium (Folinic acid)

FI5-Fluorouracil

RIIrinotecan

Indications

References

  1. “NCI Thesaurus”.
  2. 2.0 2.1 André T, Louvet C, Maindrault-Goebel F, Couteau C, Mabro M, Lotz JP; et al. (1999). “CPT-11 (irinotecan) addition to bimonthly, high-dose leucovorin and bolus and continuous-infusion 5-fluorouracil (FOLFIRI) for pretreated metastatic colorectal cancer. GERCOR”. Eur J Cancer. 35 (9): 1343–7. PMID 10658525.

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