Fatigue pathophysiology

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: M.Umer Tariq [2]

Overview

Pathophysiology

The sense of fatigue is believed to originate in the reticular activating system of the lower brain. Musculoskeletal structures may have co-evolved with appropriate brain structures so that the complete unit functions together in a constructive and adaptive fashion.^[1] The entire systems of muscles, joints, and proprioceptive and kinesthetic functions plus parts of the brain evolve and function together in a unitary way.^[2]

References

↑ Edelman, Gerald Maurice (1989). The remembered present: a biological theory of consciousness. New York: Basic Books. ISBN 0-465-06910-X.
↑ Kelso, J. A. Scott (1995). Dynamic patterns: the self-organization of brain and behavior. Cambridge, Mass: MIT Press. ISBN 0-262-61131-7.

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[1] Edelman, Gerald Maurice (1989). The remembered present: a biological theory of consciousness. New York: Basic Books. ISBN 0-465-06910-X.

[2] Kelso, J. A. Scott (1995). Dynamic patterns: the self-organization of brain and behavior. Cambridge, Mass: MIT Press. ISBN 0-262-61131-7.

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