Felty's syndrome
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., Ph.D. [2]
Overview
Felty’s syndrome is a condition characterized by the triad of rheumatoid arthritis, splenomegaly and granulocytopenia.[1]
Historical Perspective
It is named for A. R. Felty.[2][3]
Classification
Pathophysiology
Causes
Differentiating Felty’s Syndrome from Other Diseases
Epidemiology and Demographics
Age
Gender
Race
Risk Factors
Natural History, Complications and Prognosis
- Recurrent Infection,
- Hypersplenism → causing 2° anaemia ± thrombocytopenia
- Lymphadenopathy
- Skin hyperpigmentation & cutaneous ulceration
Diagnosis
Diagnostic Criteria
Symptoms
Physical Examination
Laboratory Findings
Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Treatment is similar to that of rheumatoid arthritis. Splenectomy may improve neutropenia in severe disease.
Surgery
Prevention
References
- ↑ Degowin, Elmer. Bedside Diagnositc Examiniation. MacMillan Publishing, New York. 1981. Page 894. ISBN 0023280301.
- ↑ Template:WhoNamedIt
- ↑ A. R. Felty. Chronic arthritis in the adult, associated with splenomegaly and leucopenia. A report of 5 cases of an unusual clinical syndrome. Bulletin of the Johns Hopkins Hospital, Baltimore, 1924, 35: 16.
Template:Diseases of the musculoskeletal system and connective tissue
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