Fibrin degradation product

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and Keywords: FDP

Overview

Fibrin degradation products are formed during the metabolism of fibrinogen and fibrin via plasmin. Fibrin degradation product (FDPs) are components of the blood produced by clot degeneration.^[1]

Reference Range
Fribin Degradation Products	< 1 mg/l
D-Dimers	20-400 ug/l

Differential Diagnosis

In alphabetical order. ^[2] ^[3]

Increased

Bladder carcinoma
Contact with body-foreign surfaces
Disseminated Intravascular Coagulation (DIC)
Drugs
False positive, if Rheumatoid factor is present
Fibrinolytic therapy
Postoperative
Pulmonary Embolism
Release of plasmin from plasminogen-rich organs (lungs, pancreas, prostate)
Severe Liver Disease
Subdural hematomas
Thromboses
Tumor
Venous and arterial thrombotic events

External links

MedlinePlus Encyclopedia 003655

References

↑ Gaffney PJ, Edgell T, Creighton-Kempsford LJ, Wheeler S, Tarelli E (1995). “Fibrin degradation product (FnDP) assays: analysis of standardization issues and target antigens in plasma”. Br. J. Haematol. 90 (1): 187–94. PMID 7786784.
↑ Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016
↑ Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X

Template:WikiDoc Sources

[pmid7786784-1] Gaffney PJ, Edgell T, Creighton-Kempsford LJ, Wheeler S, Tarelli E (1995). “Fibrin degradation product (FnDP) assays: analysis of standardization issues and target antigens in plasma”. Br. J. Haematol. 90 (1): 187–94. PMID 7786784.

[2] Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016

[3] Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X

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