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Focal segmental glomerulosclerosis risk factors

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Manpreet Kaur, MD [2]

Overview

Common Risk Factors

Common risk factors in the development of focal segmental glomerulosclerosis include:[1][2]

  • Male gender
  • Black race
  • Family history
  • Heroin abuse
  • HIV
  • Drugs such as pamidronate
  • Solitary kidney
  • Obesity

References

  1. Bruggeman LA, Ross MD, Tanji N, Cara A, Dikman S, Gordon RE, Burns GC, D’Agati VD, Winston JA, Klotman ME, Klotman PE (November 2000). “Renal epithelium is a previously unrecognized site of HIV-1 infection”. J. Am. Soc. Nephrol. 11 (11): 2079–87. PMID 11053484.
  2. Wyatt CM, Klotman PE, D’Agati VD (November 2008). “HIV-associated nephropathy: clinical presentation, pathology, and epidemiology in the era of antiretroviral therapy”. Semin. Nephrol. 28 (6): 513–22. doi:10.1016/j.semnephrol.2008.08.005. PMC 2656916. PMID 19013322.


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