Gallbladder cancer screening

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]

According to the National Comprehensive Cancer Network (NCCN) guidelines, gallbladder cancer may be diagnosed as an incidental finding in patients who undergo laparoscopic cholecystectomy.

• According to the NCCN guidelines, screening for gallbladder cancer patients include followings:
  • Endoscopic ultrasonography (EUS)
  • Computed tomography (CT) 
  • Magnetic resonance imaging (MRI) with/without contrast
• Patients after incidental finding during laparoscopic cholecystectomy patient are recommends considering staging laparoscopy. 
• When gallbladder pathology is suspected ultrasonography is most commonly the first choice for screening.
• Sensitivity and specificity of ultrasound screening is 85% and 80%.
• High-resolution contrast-enhanced ultrasonography identifies up to 70–90% of polypoid gallbladder lesions.^[1]

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