Ganglioglioma MRI

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Mandana Chitsazan, M.D. [2]

Overview

Brain MRI may be helpful in the diagnosis of ganglioglioma.

In MRI imaging, ganglioglioma may appear as solid or cystic lesions.
MRI T1-weighted images show a hypointense mass.
MRI T2-weighted and FLAIR images show a well-circumscribed hyperintense mass.
Ganglioglioma often does not enhance with intravenous gadolinium. However, some tumors have mild diffuse or patchy enhancement without ring appearance.
Conventionally they are sharply demarcated, but some are infiltrative and are indistinguishable from diffuse gliomas.
Anaplastic ganglioglioma is frequently infiltrative on MRI and is associated with a higher degree of gadolinium enhancement.
Overall, diagnosis might be suggested by clinical presentation and MRI characteristics, but the definitive diagnosis is only made by histopathological examination of the tumor. Review : ^[1] ^[2] ^[3]

↑ Soffietti R, Rudà R, Reardon D (2016). “Rare glial tumors”. Handb Clin Neurol. 134: 399–415. doi:10.1016/B978-0-12-802997-8.00024-4. PMID 26948368.
↑ Hayat, M. A. (2012). Tumors of the central nervous system. Dordrecht New York: Springer. ISBN 978-94-007-5487-4.
↑ Raizer, Jeffrey J.; Naidich, Michelle J. (2008). “Neuronal Tumors”: 435–448. doi:10.1016/B978-012370863-2.50045-2.