Gangrene epidemiology and demographics

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor(s)-in-Chief: Edzel Lorraine Co, D.M.D., M.D.

Overview

Ischemic or dry gangrene is commonly associated with peripheral artery disease (PAD). The most advanced stage of PAD is critical limb ischemia/ chronic limb-threatening ischemia, and it has an incidence rate of 1% in the United States. Gas gangrene is a rare condition, with an annual record of 1000 cases in the United States, 50% of which are due to traumatic injuries, 30% due to post-operative complications, and the remaining part is attributed to infections. ^[1]

Ischemic or dry gangrene is commonly associated with peripheral artery disease (PAD).
The most advanced stage of PAD is critical limb ischemia/ chronic limb-threatening ischemia, and it has an incidence rate of 1% in the United States. ^[1]
Periperhal artery disease of the lower extremities has a prevalence rate of 200 million, with up to 10% of them have critical limb ischemia/ chronic limb-threatening ischemia. ^[1]
If an asymptomatic PAD is left untreated, progression to critical limb ischemia/ chronic limb-threatening ischemia in five years. ^[1]
Gas gangrene is a rare condition, with an annual record of 1000 cases in the United States, 50% of which are due to traumatic injuries, 30% due to post-operative complications, and the remaining part is attributed to infections. ^[1]

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 Yang Z, Hu J, Qu Y, Sun F, Leng X, Li H; et al. (2015). “Interventions for treating gas gangrene”. Cochrane Database Syst Rev (12): CD010577. doi:10.1002/14651858.CD010577.pub2. PMC 8652263 Check |pmc= value (help). PMID 26631369.