Gastroesophageal reflux disease laboratory findings
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]
Overview
Laboratory findings consistent with diagnosis of GERD is the presence of acidic reflux in the esophagus through the ambulatory reflux monitoring.
Laboratory Findings
Ambulatory reflux monitoring
- GERD is mostly diagnosed clinically by the presenting typical symptoms which include heartburn, regurgitation, and dysphagia.
- Correlation of the GERD symptoms with confirmed acid presence by the ambulatory reflux monitoring is strongly suggestive of GERD.
- Ambulatory reflux monitoring is recommended by the American College of Gastroenterology (ACG) as the only laboratory test to determine the presence of acidic reflux in the esophagus.[1]
- Indications of ambulatory reflux monitoring include the following:[2]
- GERD diagnosis if it is not confirmed
- Determine the time of reflux occurrence
- Refractory GERD symptoms
- Preoperative for non-erosive disease
- Ambulatory reflux monitoring is performed in either two ways which include:
- Telemetry capsule (48 hours monitoring)
- Transnasal catheter (24 hours monitoring)
References
- ↑ Katz PO, Gerson LB, Vela MF (2013). “Guidelines for the diagnosis and management of gastroesophageal reflux disease”. Am J Gastroenterol. 108 (3): 308–28, quiz 329. doi:10.1038/ajg.2012.444. PMID 23419381.
- ↑ Katz PO, Gerson LB, Vela MF (2013). “Guidelines for the diagnosis and management of gastroesophageal reflux disease”. Am J Gastroenterol. 108 (3): 308–28, quiz 329. doi:10.1038/ajg.2012.444. PMID 23419381.
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