Gastrointestinal stromal tumor staging

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]

According to the American Joint Committee on Cancer, there are 4 stages of gastrointestinal stromal tumor based on the tumor spread.

According to the TNM (for GIST at All Sites) a formal staging system for gastrointestinal stromal tumors (GIST) appeared for the first time in the 7th edition of the American Joint Committee on Cancer (AJCC), Cancer Staging Manual. Because of the limited availability of mutation testing, mutation status is not included in the AJCC system. In addition, since nodal involvement is so rare, and nodal dissection is not indicated, the designation N0/pN0 should be used in the absence of information about the regional nodes. Note that treatment decisions may not be based strictly on the stage of disease.

• TX: Primary tumor cannot be assessed

• T0: No evidence for primary tumor

• T1: Tumor ≤2 cm

• T2: Tumor >2 cm but not >5 cm

• T3: Tumor >5 cm but not >10 cm

• T4: Tumor >10 cm in greatest dimension

• NX: Regional lymph nodes cannot be assessed

• N0: No regional lymph node metastasis

• N1: Regional lymph node metastasis

• M0: No distant metastasis

• M1: Distant metastasis

^[1]

^[2]

Template:WikiDoc Sources