Gestational diabetes laboratory findings

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Seyedmahdi Pahlavani, M.D. [2]

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Generally, a test for gestational diabetes is carried out between the 24th and 28th week of pregnancy.

If a patient is at risk for gestational diabetes (see risk factors), screening should be done earlier in the pregnancy.

Depending on the woman’s risk and her previous test results, she may have one or more of the following tests.^[1]

• Screening glucose test
• Oral glucose tolerance test (OGTT)

There are several tests intended to identify gestational diabetes in pregnant women. ^[2][3]

• The first, called the screening glucose challenge test, is a preliminary screening test performed between 24-28 weeks. If a woman tests positive during this screening test, a second test called the Glucose Tolerance Test, may be performed.
• The second test confirms the diagnoses.

The screening glucose challenge test is now considered as the standard test performed during the second trimester of pregnancy.

Women who are considered at risk for gestational diabetes are given a screening test called a 50 gram glucose challenge between the 24th and 28th weeks of pregnancy (those with two or more risk factors may be tested earlier). The glucose challenge is performed by giving 50 grams of a glucose drink and then drawing a blood sample one hour later to measure the level of blood glucose present. Women with a blood sugar level greater than 140 mg/dl may have gestational diabetes, and require a follow-up test called a 3-hour oral glucose tolerance test (OGTT). ^[4][2][3]

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