Gestational trophoblastic neoplasia surgery

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Monalisa Dmello, M.B,B.S., M.D. [2]

Surgery is the mainstay of treatment for choriocarcinoma.

Surgery is one of the main treatments for gestational trophoblastic neoplasia.^[1] The indication for surgery include:

• Primary treatment for gestational trophoblastic neoplasia
• Recurrence of gestational trophoblastic neoplasia after other treatments

Hysterectomy

• Hysterectomy may be offered to women with gestational trophoblastic neoplasia that has not spread outside of the uterus and who no longer wish to have children.
• Hysterectomy may also be recommended to women with gestational trophoblastic neoplasia that does not respond to chemotherapy.
• Hysterectomy is the primary treatment for women with placental site trophoblastic tumours because this type of cancer does not respond well to chemotherapy.

• Surgery may be done for gestational trophoblastic neoplasia that has spread to distant sites in the body, such as the brain, intestines, kidneys, liver, lungs, and spleen.
• In the case of brain metastases, surgery may only be done if a tumor is close to the surface of the brain.

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