Glucose-6-phosphate dehydrogenase deficiency natural history, complications and prognosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mahda Alihashemi M.D. [2]

Overview

The symptoms of G6PD deficiency typically develop after exposure to some foods and medications. Common complications of G6PD deficiency include acute hemolytic anemia and neonatal jaundice.

Natural History, Complications, and Prognosis

Natural History

The symptoms of G6PD deficiency typically develop after exposure to some foods and medications.

Complications

Common complications of G6PD deficiency include:^[1]
- Acute hemolytic anemia
- Neonatal jaundice
- Acute kidney failure

Prognosis

Prognosis is generally good.^[2]

References

↑ Luzzatto L, Nannelli C, Notaro R (April 2016). “Glucose-6-Phosphate Dehydrogenase Deficiency”. Hematol. Oncol. Clin. North Am. 30 (2): 373–93. doi:10.1016/j.hoc.2015.11.006. PMID 27040960.
↑ Bubp J, Jen M, Matuszewski K (September 2015). “Caring for Glucose-6-Phosphate Dehydrogenase (G6PD)-Deficient Patients: Implications for Pharmacy”. P T. 40 (9): 572–4. PMC 4571844. PMID 26417175.

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[pmid27040960-1] Luzzatto L, Nannelli C, Notaro R (April 2016). “Glucose-6-Phosphate Dehydrogenase Deficiency”. Hematol. Oncol. Clin. North Am. 30 (2): 373–93. doi:10.1016/j.hoc.2015.11.006. PMID 27040960.

[pmid26417175-2] Bubp J, Jen M, Matuszewski K (September 2015). “Caring for Glucose-6-Phosphate Dehydrogenase (G6PD)-Deficient Patients: Implications for Pharmacy”. P T. 40 (9): 572–4. PMC 4571844. PMID 26417175.

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