Glucose-6-phosphate dehydrogenase deficiency risk factors

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mahda Alihashemi M.D. [2]

Common risk factors in the development of G6PD deficiency include some foods such as fava beans, some medications and infections.

Common risk factors in the development of G6PD deficiency include some foods such as fava beans, some medications and infections.

• Common risk factors in the development of G6PD include:
  • Foods such as fava beans in G6PD mutation carriers
  • Medications ^[1]
    • Aspirin
    • Antimalarials: quinine, primaquine, pamaquine, and chloroquine
    • Sulfonamides: mafenide, sulfanilamide, sulfamethoxazole
    • Thiazolesulfone
    • Methylene blue
    • Analgesics: phenazopyridine and acetanilide
    • Rasburicase
    • Some non-sulfa antibiotics such as furazolidone, isoniazid, dapsone, nalidixic acid, nitrofurantoin).
    • High dose vitamin C
  • Bacterial, viral and rickettsial infection
  • Some chemicals: Hanna in tattos and hair dyes^[2]

• Less common risk factors in the development of G6PD include:
  • Moth balls (naphthalene)
  • Diabetic ketoacidosis^[3]
  • Amyl nitrite or isobutyl nitrite in RUSH ( sexual enhancement drug)^[4]

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