Gonadal dysgenesis
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Gonadal dysgenesis generally refers to a condition where gonadal development is abnormal, often only presenting streaks of connective tissue: so-called streak gonads.
Etiology
The condition may be due to:
- Turner syndrome, and its variations (i.e. mosaicism)
- XX gonadal dysgenesis, also pure gonadal dysgenesis, 46, XX
- Swyer syndrome, also pure gonadal dysgenesis, 46, XY
- Perrault syndrome
- Mixed gonadal dysgenesis
- Endocrine disruptors
Presentation
It is one of the causes of intersexuality, because the genitalia are determined to be neither exclusively male nor female.
See also
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