HIV associated nephropathy diagnostic study of choice

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Ali Poyan Mehr, M.D. [2];Associate Editor(s)-in-Chief: Shakiba Hassanzadeh, MD [3]Krzysztof Wierzbicki M.D. [4]

Overview

Renal biopsy is the diagnostic study of choice for HIV-associated nephropathy (HIVAN). Renal biopsy reveals the following findings: collapsing focal segmental glomerulonephritis, significant tubulointerstitial injury, interstitial fibrosis and inflammation and microcystic tubular dilation.

HIV associated nephropathy Diagnostic Study of Choice

Renal Biopsy

Renal biopsy is the diagnostic study of choice for HIV-associated nephropathy (HIVAN).

Renal biopsy is an essential tool for evaluation and identification of HIV-associated and other kidney diseases in HIV-positive patients, which is important in the management and treatment of the patients.^[1]
Renal biopsy reveals the following findings in HIVAN:^[2]
- Collapsing focal segmental glomerulonephritis
- Significant tubulointerstitial injury
- Interstitial fibrosis and inflammation
- Microcystic tubular dilation

References

↑ Fine DM, Perazella MA, Lucas GM, Atta MG (2008). “Kidney biopsy in HIV: beyond HIV-associated nephropathy”. Am J Kidney Dis. 51 (3): 504–14. doi:10.1053/j.ajkd.2007.12.005. PMID 18295067.
↑ D’Agati V, Suh JI, Carbone L, Cheng JT, Appel G (1989). “Pathology of HIV-associated nephropathy: a detailed morphologic and comparative study”. Kidney Int. 35 (6): 1358–70. PMID 2770114.

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[pmid18295067-1] Fine DM, Perazella MA, Lucas GM, Atta MG (2008). “Kidney biopsy in HIV: beyond HIV-associated nephropathy”. Am J Kidney Dis. 51 (3): 504–14. doi:10.1053/j.ajkd.2007.12.005. PMID 18295067.

[pmid2770114-2] D’Agati V, Suh JI, Carbone L, Cheng JT, Appel G (1989). “Pathology of HIV-associated nephropathy: a detailed morphologic and comparative study”. Kidney Int. 35 (6): 1358–70. PMID 2770114.

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