HLA-A11

HLA-A11 (A11) is an HLA–A serotype. The serotype identifies the more common HLA-A*11 gene products. A11 is more common in eastern Asia particularly along the coastal regions of china.

Serotype

A11 serotype recognition of Some HLA A*11 allele-group gene products^[1]
A*11	A11	A10	Sample
allele	%	%	size (N)
*1101	99		2530
*1102	76		42
*1103	83		18
*1104	60		6
*1105	66	33	3

Serotyping of A11 demostrates better recognition of the *1101 gene products and poorer recognition of other A*11 gene products. Ther are ~40 recognized alleles of A*11. There is only one null classified as A11.

Disease Associations

By allele

A*1104 is associated with increased risk for cervical neoplasia resulting from human papillomavirus infection^[2]

A11-B Haplotypes

A11-B13

A11-Cw2-B13 (Li)
A11-Cw9-B13 (Southern China & SE Asia)
A11-C10-B13 Buyi
A11-CBL-B13 Northern China

References

↑ derived from IMGT/HLA
↑ Chan D, Cheung T, Tam A, Cheung J, Yim S, Lo K, Siu N, Zhou D, Chan P (2005). “Risk association between human leukocyte antigen-A allele and high-risk human papillomavirus infection for cervical neoplasia in Chinese women”. J Infect Dis. 192 (10): 1749–56. PMID 16235173.

Template:WikiDoc Sources

[1] rived from IMGT/HLA

[2] Chan D, Cheung T, Tam A, Cheung J, Yim S, Lo K, Siu N, Zhou D, Chan P (2005). “Risk association between human leukocyte antigen-A allele and high-risk human papillomavirus infection for cervical neoplasia in Chinese women”. J Infect Dis. 192 (10): 1749–56. PMID 16235173.

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