HLA-A74

HLA-A74 (A74) is an HLA–A serotype. The serotype identifies the HLA-A*7401 gene product. A74 is a split antigen type of the A19 broad antigen type. A74 is rare.

Serotype

A74, A19 serotype recognition of Some HLA A*74 allele-group gene products^[1]
A*74	A74	A19	Sample
allele	%	%	size (N)
7401	40	11	119
7401	17		29

Disease associations

A significant association has been found between A74 and nasal polyposis.^[2]

A*74 allele Frequencies

HLA A*7401 frequencies
		freq
ref.	Population	(%)
^[3]	Kenya	9.7
^[3]	Cameroon Beti	8.3
^[3]	Guinea Bissau	7.7
^[3]	Burkina Faso Mossi	6.6
^[3]	Uganda Kampala	5.2
^[3]	Cameroon Yaounde	5.0
^[3]	Cameroon Bamileke	4.5
^[3]	Cameroon Sawa	3.8
^[3]	Mali Bandiagara	3.6
^[3]	Iran Baloch	2.8
^[3]	Zimbabwe Harare Shona	2.7
^[3]	Senegal Niokholo Mandenka	2.2
^[3]	Burkina Faso Rimaibe	2.1
^[3]	Kenya Nandi	1.7
^[3]	Morocco Nador Metalsa	1.4
^[3]	Thailand Northeast	1.2
^[3]	Thailand	1.1
^[3]	Jordon Amman	0.7
^[3]	Jordon Amman	0.5
^[3]	China South	0.5

HLA A*7403 frequencies
		freq
ref.	Population	(%)
^[3]	Kenya Luo	7.3
^[3]	Iran Baloch	0.6
^[3]	Kenya	0.3
^[3]	Uganda Kampala	0.3

References

↑ derived from IMGT/HLA
↑ Luxenberger W, Posch U, Berghold A, Hofmann T, Lang-Loidolt D (2000). “HLA patterns in patients with nasal polyposis”. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology – Head and Neck Surgery. 257 (3): 137–9. PMID 10839486.
↑ ^3.00 ^3.01 ^3.02 ^3.03 ^3.04 ^3.05 ^3.06 ^3.07 ^3.08 ^3.09 ^3.10 ^3.11 ^3.12 ^3.13 ^3.14 ^3.15 ^3.16 ^3.17 ^3.18 ^3.19 ^3.20 ^3.21 ^3.22 ^3.23 Middleton D, Menchaca L, Rood H, Komerofsky R (2003). “New allele frequency database: http://www.allelefrequencies.net“. Tissue Antigens. 61 (5): 403–7. PMID 12753660. External link in |title= (help)

Template:WikiDoc Sources

[1] rived from IMGT/HLA

[pmid10839486-2] Luxenberger W, Posch U, Berghold A, Hofmann T, Lang-Loidolt D (2000). “HLA patterns in patients with nasal polyposis”. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology – Head and Neck Surgery. 257 (3): 137–9. PMID 10839486.

[pmid12753660-3] 3.00 ^3.01 ^3.02 ^3.03 ^3.04 ^3.05 ^3.06 ^3.07 ^3.08 ^3.09 ^3.10 ^3.11 ^3.12 ^3.13 ^3.14 ^3.15 ^3.16 ^3.17 ^3.18 ^3.19 ^3.20 ^3.21 ^3.22 ^3.23 Middleton D, Menchaca L, Rood H, Komerofsky R (2003). “New allele frequency database: http://www.allelefrequencies.net“. Tissue Antigens. 61 (5): 403–7. PMID 12753660. External link in |title= (help)

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