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Headache natural history, complications and prognosis

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Editor-In-Chief: Robert G. Schwartz, M.D. [1], Piedmont Physical Medicine and Rehabilitation, P.A.; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]

Overview

The symptoms of cluster headache usually decreased with age.13% of patients with initial episodic cluster headache may progress to develop chronic cluster headache.33% of patients with initial episodic cluster headache may progress to episodic pattern.

Natural History, Complications, and Prognosis

Natural History

  • The symptoms of cluster headache usually decreased with age.
  • 13% of patients with initial episodic cluster headache may progress to develop chronic cluster headache.
  • 33% of patients with initial episodic cluster headache may progress to episodic pattern.[1]

Complications

  • Status migrainosus: The migraine episode lasts more than 72 hours.
  • Persistent aura without infarction: The symptoms of aura last for more than a week in the absence of any neuroimaging findings suggestive of infarction.
  • Migrainous infarction: The symptoms of aura last for more than a week in the context of any neuroimaging findings suggestive of infarction in the corresponding brain territory.
  • Seizure triggered by a migrainous aura[2]

Prognosis

  • 13% of patients with initial episodic cluster headache may progress to develop chronic cluster headache.
  • 33% of patients with initial episodic cluster headache may progress to episodic pattern.[1]

References

  1. 1.0 1.1 Wei DY, Yuan Ong JJ, Goadsby PJ (2018). “Cluster Headache: Epidemiology, Pathophysiology, Clinical Features, and Diagnosis”. Ann Indian Acad Neurol. 21 (Suppl 1): S3–S8. doi:10.4103/aian.AIAN_349_17. PMC 5909131. PMID 29720812.
  2. Headache Classification Committee of the International Headache Society (IHS) (2013). “The International Classification of Headache Disorders, 3rd edition (beta version)”. Cephalalgia. 33 (9): 629–808. doi:10.1177/0333102413485658. PMID 23771276.

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References

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