Heartburn risk factors
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: José Eduardo Riceto Loyola Junior, M.D.[2]
Overview
Common risk factors in the development of heartburn as a consequence of gastroesophageal reflux disease (GERD) are obesity, increasing age, smoking, hiatal hernia, white bread, chocolate, mint, cinnamon, carbonated beverages, fatty foods, alcohol, wine and beer.
Less common risk factors include certain genetic changes.
Common Heartburn Risk Factors
- Common risk factors in the development of heartburn as a consequence of gastroesophageal reflux disease (GERD) are obesity, increasing age, smoking, hiatal hernia, white bread, chocolate, mint, cinnamon, carbonated beverages, fatty foods, alcohol, wine and beer.
- Exercising and coffee intake were considered protective factors.[1]
- Women experience heartburn generally 5 years later than men.[2]
| Risk Factors: |
|---|
| Obesity |
| Age |
| Smoking |
| Hiatal Hernia |
| Dietary Risk Factors |
| White bread |
| Chocolate |
| Mint |
| Cinnamon |
| Carbonated beverages |
| Fatty foods |
| Alcohol – Wine and ber |
| Genetic Risk Factors |
| C allele in FOX1 rs9936833 – ↑ reflux symptoms |
| A allele in MHC rs9257809 – ↑ reflux symptoms |
| rs10419226 (chr 19) – ↑GERD symptoms |
| rs2687201 (chr 3) ↑GERD symptoms |
| ABHD10, RNF7, RASGRF2, BTF3P7, C8orf4, GLDC, and ADAMTS17 |
References
- ↑ 1.0 1.1 Argyrou A, Legaki E, Koutserimpas C, Gazouli M, Papaconstantinou I, Gkiokas G; et al. (2018). “Risk factors for gastroesophageal reflux disease and analysis of genetic contributors”. World J Clin Cases. 6 (8): 176–182. doi:10.12998/wjcc.v6.i8.176. PMC 6107529. PMID 30148145.
- ↑ Oliveria SA, Christos PJ, Talley NJ, Dannenberg AJ (1999). “Heartburn risk factors, knowledge, and prevention strategies: a population-based survey of individuals with heartburn”. Arch Intern Med. 159 (14): 1592–8. doi:10.1001/archinte.159.14.1592. PMID 10421282.
- ↑ Raibrown A, Giblin LJ, Boyd LD, Perry K (2017). “Gastroesophageal Reflux Disease Symptom Screening in a Dental Setting”. J Dent Hyg. 91 (1): 44–48. PMID 29118150.
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