Hemochromatosis primary prevention
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sunny Kumar MD [2]
Overview
There is no primary prevention of inherited hemochormatosis. However conditions causing secondary iron load can be avoided. Screening family members of a person diagnosed with hemochromatosis may detect the disease early so that treatment can be started before organ damage has occurred in other affected relatives.
Primary Prevention
There is no primary prevention of inherited hemochormatosis. However conditions causing secondary iron load can be avoided. Screening family members of a person diagnosed with hemochromatosis may detect the disease early so that treatment can be started before organ damage has occurred in other affected relatives.
| Measurements | Asymptomatic | Symptomatic |
|---|---|---|
| Serum iron level (μg/dL) | 150-280 | 180-300 |
| Serum transferrin saturation | 45-100 | 80-100 |
| Serum ferritin level (μg/L) | Men 150-1000 | 500-6000 |
| Female 120-1000 | 500-6000 | |
| Hepatic iron concentration μg/g dry weight | 2000-10,000 | 8000-30,000 |
| Perls’ Prussian blue stain | 2+ to 4+ | 3+, 4+ |
| Hepatic iron index | >1.9 | >1.9 |
References
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