Hemophagocytic lymphohistiocytosis overview
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Hemophagocytic lymphohistiocytosis (HLH) is an uncommon hematologic disorder in which the immune system produces too many activated immune cells (lymphocytes) called T cells, natural killer cells, B cells, and macrophages (histiocytes). Excessive amounts of immune system proteins called cytokines are also produced.
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Hemophagocytic lymphohistiocytosis overview from Other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications, and Prognosis
Natural History
Complications
Prognosis
Diagnosis
Diagnostic Criteria
History and Symptoms
Physical Examination
Laboratory Findings
Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Prevention
References
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