High IDL causes
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ogheneochuko Ajari, MB.BS, MS [2]
Overview
Disorders that would increase or cause high IDL may be due to defects or deficiency in the lipoprotein particle, endocrine causes, familial and metabolic causes.
Causes
Life Threatening Causes
Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.
There are no life threatening causes of high IDL.
Common Causes
Causes by Organ System
| Cardiovascular | Hypocalcemia, Reaven X syndrome |
| Chemical/Poisoning | No underlying causes |
| Dental | No underlying causes |
| Dermatologic | No underlying causes |
| Drug Side Effect | No underlying causes |
| Ear Nose Throat | No underlying causes |
| Endocrine | Diabetes mellitus type 2, diabetic nephropathy, hyperparathyroidism, hypocalcemia, Reaven X syndrome |
| Environmental | No underlying causes |
| Gastroenterologic | Glycogen storage disease type 1a |
| Genetic | Apolipoprotein E deficiency, decreased hepatic triglyceride lipase, familial alphalipoprotein deficiency, glycogen storage disease type 1a, Reaven X syndrome |
| Hematologic | No underlying causes |
| Iatrogenic | No underlying causes |
| Infectious Disease | No underlying causes |
| Musculoskeletal/Orthopedic | No underlying causes |
| Neurologic | No underlying causes |
| Nutritional/Metabolic | Glycogen storage disease type 1a, hypocalcemia, Reaven X syndrome |
| Obstetric/Gynecologic | No underlying causes |
| Oncologic | No underlying causes |
| Ophthalmologic | Diabetes mellitus type 2 |
| Overdose/Toxicity | No underlying causes |
| Psychiatric | No underlying causes |
| Pulmonary | No underlying causes |
| Renal/Electrolyte | Chronic renal failure, diabetes mellitus type 2, diabetic nephropathy, hypocalcemia |
| Rheumatology/Immunology/Allergy | Reaven syndrome X |
| Sexual | No underlying causes |
| Trauma | No underlying causes |
| Urologic | No underlying causes |
| Miscellaneous | No underlying causes |
Causes in Alphabetical Order
- Apolipoprotein E deficiency
- Chronic renal failure [1]
- Decreased hepatic triglyceride lipase[2][3]
- Diabetes mellitus type 2 [4]
- Diabetic nephropathy[5]
- Familial alphalipoprotein deficiency
- Glycogen storage disease type 1a[6][7]
- Hyperparathyroidism [2]
- Hypocalcemia [2]
- Reaven X syndrome
References
- ↑ Nishizawa Y, Shoji T, Tabata T, Inoue T, Morii H (1999). “Effects of lipid-lowering drugs on intermediate-density lipoprotein in uremic patients”. Kidney Int Suppl. 71: S134–6. PMID 10412757.
- ↑ 2.0 2.1 2.2 Nishizawa Y, Shoji T, Kawagishi T, Morii H (1997). “Atherosclerosis in uremia: possible roles of hyperparathyroidism and intermediate density lipoprotein accumulation”. Kidney Int Suppl. 62: S90–2. PMID 9350691.
- ↑ Oi K, Hirano T, Sakai S, Kawaguchi Y, Hosoya T (1999). “Role of hepatic lipase in intermediate-density lipoprotein and small, dense low-density lipoprotein formation in hemodialysis patients”. Kidney Int Suppl. 71: S227–8. PMID 10412783.
- ↑ Durrington PN (1993). “Diabetes, hypertension and hyperlipidaemia”. Postgrad Med J. 69 Suppl 1: S18–25, discussion S25-9. PMID 8497453.
- ↑ Shoji T, Emoto M, Kawagishi T, Kimoto E, Yamada A, Tabata T; et al. (2001). “Atherogenic lipoprotein changes in diabetic nephropathy”. Atherosclerosis. 156 (2): 425–33. PMID 11395040.
- ↑ Geberhiwot T, Alger S, McKiernan P, Packard C, Caslake M, Elias E; et al. (2007). “Serum lipid and lipoprotein profile of patients with glycogen storage disease types I, III and IX”. J Inherit Metab Dis. 30 (3): 406. doi:10.1007/s10545-007-0485-2. PMID 17407002.
- ↑ Levy E, Thibault LA, Roy CC, Bendayan M, Lepage G, Letarte J (1988). “Circulating lipids and lipoproteins in glycogen storage disease type I with nocturnal intragastric feeding”. J Lipid Res. 29 (2): 215–26. PMID 3130454.
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