Hyperparathyroidism classification

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anmol Pitliya, M.B.B.S. M.D.[2]

Hyperparathyroidism can be classified according to origin of defect into primary, secondary and tertiary.

Hyperparathyroidism can be classified according to origin of defect into primary, secondary and tertiary.

• Primary hyperparathyroidism is due to over activity of the parathyroid glands themselves. The most important causes of oversecretion of parathyroid hormone include:
• Adenoma
• Hyperplasia
• Carcinoma of the parathyroid glands

Secondary hyperparathyroidism is due to increase in secretion of parathyroid hormone from a secondary process.

Tertiary hyperparathyroidism is a state of excessive secretion of parathyroid hormone (PTH) after a long period of secondary hyperparathyroidism and resulting in hypercalcemia even after treatment of secondary hyperparathyroidism.

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