Hypogonadism classification

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]

Overview

Hypogonadism may be classified according to the etiological site into three subtypes namely primary, secondary or combined. Hypogonadism can also be classified according to the age into two adult and child onset disease. Also, it could be classified based on the causes into acquired or congenital.^[1]

Classification

Based on the location, hypogonadism can be classified into:
- Primary: gonads (ovaries or testes) are the primary source of the pathology.
- Secondary (central): If the cause of the disease is the hypothalamus or pituitary.
- Combined

Based on the age, hypogonadism can be classified into:
- Childhood onset hypogonadism
- Adult onset hypogonadism

Based on the causes of the disease, hypogonadism can be classified into:
- Acquired hypogonadism
- Congenital hypogonadism

References

↑ Rey RA, Grinspon RP, Gottlieb S, Pasqualini T, Knoblovits P, Aszpis S; et al. (2013). “Male hypogonadism: an extended classification based on a developmental, endocrine physiology-based approach”. Andrology. 1 (1): 3–16. doi:10.1111/j.2047-2927.2012.00008.x. PMID 23258624.

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[pmid23258624-1] Rey RA, Grinspon RP, Gottlieb S, Pasqualini T, Knoblovits P, Aszpis S; et al. (2013). “Male hypogonadism: an extended classification based on a developmental, endocrine physiology-based approach”. Andrology. 1 (1): 3–16. doi:10.1111/j.2047-2927.2012.00008.x. PMID 23258624.

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