Hypotension medical therapy

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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The treatment for hypotension depends on its cause. Asymptomatic hypotension in healthy people usually does not require treatment. Severe hypotension needs to be aggressively treated because reduced blood flow to critical organs including the brain, heart and kidneys may cause organ failure and can ultimately lead to death. Treatment options include systemic vasoconstrictors and other drugs.

• Increase salt and water intake
• Caffeine
• Fluid replacement
• Remove harmful/offending medications
• Educate patient
• Fludrocortisone acetate
• Sympathomimetic agents
• Nonsteriodal anti-inflammatory drugs (NSAIDs)
• Erythropoietin
• IV hydrocortisone

Hypotension (systolic pressure less than 90 mm Hg) is considered an absolute contraindication to the use of the following medications:

• Verapamil
• Diltiazem
• Labetalol
• Propafenone

Persistent systolic blood pressure <100 mm Hg is considered an absolute contraindication to the use of the following medications:

• Nesiritide

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