Inguinal hernia medical therapy

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Farima Kahe M.D. [2]

Pharmacologic medical therapies for inguinal hernia include pain reliever, antibiotics, topical medications.

• Pharmacologic medical therapies for patients with post-operative repair of inguinal hernia include:^[1][2][3][4]
  • 1. Pain reliever
    • Preferred regimen: Non-steroidal anti-inflammatory drugs(NSAIDs) 400mg PO q12h PRN
    • Alternative regimen (1) Gabapentin 300 mg PO q 8h PRN
    • Alternative regimen (2): Pregabalin 300 mg PO q 8h PRN
    • Alternative regimen (5): Opioids 2-10 mg IV q 2-4h PRN
    • Alternative regimen (6): Tramadol 50-100 mg PO q 4-6h PRN
    • Alternative regimen (3): Duloxetine 30 mg PO q 24h for 1 week
    • Alternative regimen (4): Venlafaxine 75-225 mg PO q 24h for 1 week
  • 2. Antibiotics
    • Preferred regimen: Cefazolin 2 g IV for 7 days
    • Alternative regimen (1): Clindamycin 900 mg q 8h for 7 days
    • Alternative regimen (2): Vancomycin 15 mg/kg IV for 7-10 days
    • Alternative regimen (3): Ciprofloxacin 400 mg IV for 10 days
    • Alternative regimen (4): levofloxacin 500 mg IV for 5 days
    • Alternative regimen (5): Aztreonam 2 g IV q 6-8h (not to exceed 8g/day)
  • 3. Topical medications
    • Lidocaine
    • Capsaicin’s analgesic

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