Jaundice and RUQ pain differential diagnosis are:
| Classification of jaundice based on etiology
|
Disease
|
History and clinical manifestations
|
Diagnosis
|
| Lab Findings
|
Other blood tests
|
Other diagnostic
|
| Family history
|
Fever
|
RUQ Pain
|
Pruritis
|
AST
|
ALT
|
ALK
|
BLR Indirect
|
BLR Direct
|
Viral serology
|
| Jaundice
|
Hepatocellular Jaundice
|
Hemochromatosis
|
+
|
–
|
-/+
|
–
|
↑
|
↑
|
↑/N
|
↑/N
|
N
|
–
|
Ferritin ↑
|
Liver biopsy
|
| Wilson’s disease
|
+
|
–
|
-/+
|
–
|
↑
|
↑
|
N
|
↑/N
|
N
|
–
|
Serum cerulloplasmin ↑
|
Liver biopsy
|
| Alcoholic hepatitis
|
–
|
-/+
|
-/+
|
–
|
↑↑
|
↑
|
N
|
↑/N
|
N
|
–
|
–
|
–
|
| Cirrhosis
|
-/+
|
-/+
|
-/+
|
–
|
↑
|
↑
|
↑/N
|
↑/N
|
↑/N
|
-/+
|
Low platate
|
Small liver on ultrasond
|
| Cholestatic Jaundice
|
Common bile duct stone
|
-/+
|
–
|
+
|
+
|
N
|
N
|
↑
|
N
|
↑
|
–
|
Dilated ducts on sono
|
CT/ERCP
|
| Hepatitis A cholestatic type
|
–
|
-/+
|
+
|
+
|
N
|
N
|
↑
|
N
|
↑
|
+
|
HAV- AB
|
Abdominal ultrasound
|
| EBV / CMV hepatitis
|
–
|
-/+
|
+
|
+
|
N
|
N
|
↑
|
N
|
↑
|
+
|
Positive serology
|
|
| Primary biliary cirrhosis
|
-/+
|
–
|
-/+
|
+
|
N/↑
|
N/↑
|
↑
|
N
|
↑
|
–
|
AMA positive
|
Liver biopsy
|
| Primary sclerosing cholangitis
|
-/+
|
–
|
-/+
|
+
|
N/↑
|
N/↑
|
↑
|
N
|
↑
|
–
|
Beading on MRCP
|
Liver biopsy
|
| Pancreatic carcinoma
|
+
|
–
|
-/+
|
–
|
N/↑
|
N/↑
|
↑
|
N
|
↑
|
–
|
Mass on ultrasond
|
CT scan for diagnosis
|
|
