Kawasaki disease other diagnostic studies

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dildar Hussain, MBBS [2]

Overview

Urinalysis, lumbar puncture, biomarkers evaluation, and angiography may be helpful in the diagnosis of Kawasaki disease.

Other diagnostic tests include:^[1]

Urinalysis
- May demonstrate white blood cells and protein in the urine (sterile pyuria and proteinuria, respectively) without any evidence of bacterial growth.
Lumbar puncture
- May demonstrate evidence of aseptic meningitis.
Angiography
- May be used to detect coronary artery aneurysms and remains the gold standard for their detection, but is rarely used today unless coronary artery aneurysms have already been detected by echocardiography.
Biomarkers
- Soluble LR11 may provide evidence of vascular lesions in Kawasaki disease.

↑ Watanabe K, Suzuki H, Jiang M, Haniu H, Numano F, Hoshina S, Saitoh A, Uchiyama M, Bujo H (March 2016). “Soluble LR11 is a novel biomarker for vascular lesions late after Kawasaki disease”. Atherosclerosis. 246: 94–7. doi:10.1016/j.atherosclerosis.2015.12.035. PMID 26761773.