LMLN
Leishmanolysin-like (metallopeptidase M8 family) is a protein that in humans is encoded by the LMLN gene.[1]
Function
This gene encodes a zinc-metallopeptidase. The encoded protein may play a role in cell migration and invasion. Studies of a similar protein in Drosophila indicate a potential role in mitotic progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009].
References
Further reading
- Cobbe N, Marshall KM, Gururaja Rao S, Chang CW, Di Cara F, Duca E, Vass S, Kassan A, Heck MM (September 2009). “The conserved metalloprotease invadolysin localizes to the surface of lipid droplets”. Journal of Cell Science. 122 (Pt 18): 3414–23. doi:10.1242/jcs.044610. PMC 2736869. PMID 19706689.
- McHugh B, Krause SA, Yu B, Deans AM, Heasman S, McLaughlin P, Heck MM (November 2004). “Invadolysin: a novel, conserved metalloprotease links mitotic structural rearrangements with cell migration”. The Journal of Cell Biology. 167 (4): 673–86. doi:10.1083/jcb.200405155. PMC 2172566. PMID 15557119.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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