Langerhans cell histiocytosis physical examination

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]

Overview

Langerhans cell histiocytosis patients often appear cachectic. Physical examination of patients with Langerhans cell histiocytosis is usually remarkable for scaly erythematous lesions located on the scalp and extremities, localized bone tenderness, and hepatosplenomegaly.^[1]^[2]

Physical Findings

General Appearance

Langerhans cell histiocytosis patients often appear cachectic^[3]

Vital Signs

Low-grade fever^[4]

HEENT

Scaly erythematous scalp lesions

Abdomen

Extremities

Scaly erythematous cutaneous lesions
Localized bone tenderness

Gallery

Langerhans cell histiocytosis. Adapted from Dermatology Atlas.^[5]
Langerhans cell histiocytosis. Adapted from Dermatology Atlas.^[5]
Langerhans cell histiocytosis. Adapted from Dermatology Atlas.^[5]
Langerhans cell histiocytosis. Adapted from Dermatology Atlas.^[5]
Langerhans cell histiocytosis. Adapted from Dermatology Atlas.^[5]
Langerhans cell histiocytosis. Adapted from Dermatology Atlas.^[5]

Langerhans cell histiocytosis. Adapted from Dermatology Atlas.^[5]
Langerhans cell histiocytosis. Adapted from Dermatology Atlas.^[5]
Langerhans cell histiocytosis. Adapted from Dermatology Atlas.^[5]

References

↑ Langerhans Cell Histiocytosis Treatment (PDQ®): Health Professional Version. National Cancer Institute (2015) http://www.cancer.gov/types/langerhans/hp/langerhans-treatment-pdq Accessed on February, 3 2016
↑ Langerhans cell histiocytosis. Wikipedia (2015) https://en.wikipedia.org/wiki/Langerhans_cell_histiocytosis Accessed on February, 2 2016
↑ Riccardo Haupt, Milen Minkov, Itziar Astigarraga, Eva Schafer, Vasanta Nanduri, Rima Jubran, R. Maarten Egeler, Gritta Janka, Dragan Micic, Carlos Rodriguez-Galindo, Stefaan Van Gool, Johannes Visser, Sheila Weitzman & Jean Donadieu (2013). “Langerhans cell histiocytosis (LCH): guidelines for diagnosis, clinical work-up, and treatment for patients till the age of 18 years”. Pediatric blood & cancer. 60 (2): 175–184. doi:10.1002/pbc.24367. PMID 23109216. Unknown parameter |month= ignored (help)
↑ Tetsuko Kobayashi, Yuhki Koga, Masataka Ishimura, Kentaro Nakashima, Wakako Kato, Hiroaki Ono, Motoshi Sonoda, Katsuhide Eguchi, Reiji Fukano, Satoshi Honjo, Yoshinao Oda & Shouichi Ohga (2018). “Fever and Skin Involvement at Diagnosis Predicting the Intractable Langerhans Cell Histiocytosis: 40 Case-Series in a Single Center”. Journal of pediatric hematology/oncology. 40 (3): e148–e153. doi:10.1097/MPH.0000000000001080. PMID 29293189. Unknown parameter |month= ignored (help)
↑ ^5.0 ^5.1 ^5.2 ^5.3 ^5.4 ^5.5 ^5.6 ^5.7 ^5.8 “Dermatology Atlas”.

Template:WikiDoc Sources

[PDQ-1] Langerhans Cell Histiocytosis Treatment (PDQ®): Health Professional Version. National Cancer Institute (2015) http://www.cancer.gov/types/langerhans/hp/langerhans-treatment-pdq Accessed on February, 3 2016

[wiki-2] Langerhans cell histiocytosis. Wikipedia (2015) https://en.wikipedia.org/wiki/Langerhans_cell_histiocytosis Accessed on February, 2 2016

[3] Riccardo Haupt, Milen Minkov, Itziar Astigarraga, Eva Schafer, Vasanta Nanduri, Rima Jubran, R. Maarten Egeler, Gritta Janka, Dragan Micic, Carlos Rodriguez-Galindo, Stefaan Van Gool, Johannes Visser, Sheila Weitzman & Jean Donadieu (2013). “Langerhans cell histiocytosis (LCH): guidelines for diagnosis, clinical work-up, and treatment for patients till the age of 18 years”. Pediatric blood & cancer. 60 (2): 175–184. doi:10.1002/pbc.24367. PMID 23109216. Unknown parameter |month= ignored (help)

[4] Tetsuko Kobayashi, Yuhki Koga, Masataka Ishimura, Kentaro Nakashima, Wakako Kato, Hiroaki Ono, Motoshi Sonoda, Katsuhide Eguchi, Reiji Fukano, Satoshi Honjo, Yoshinao Oda & Shouichi Ohga (2018). “Fever and Skin Involvement at Diagnosis Predicting the Intractable Langerhans Cell Histiocytosis: 40 Case-Series in a Single Center”. Journal of pediatric hematology/oncology. 40 (3): e148–e153. doi:10.1097/MPH.0000000000001080. PMID 29293189. Unknown parameter |month= ignored (help)

[Dermatology_Atlas-5] 5.0 ^5.1 ^5.2 ^5.3 ^5.4 ^5.5 ^5.6 ^5.7 ^5.8 “Dermatology Atlas”.

[1]

[2]

[3]

[4]

[5]