Laron syndrome history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Symptoms
The principal feature of Laron syndrome is abnormally short stature (dwarfism). Symptoms include:
- Truncal obesity[1]
- Seizures are frequently secondary to hypoglycemia.
- Some genetic variations have an impact upon intellectual capacity.[2]
References
- ↑ Laron Z, Ginsberg S, Lilos P, Arbiv M, Vaisman N (2006). “Body composition in untreated adult patients with Laron syndrome (primary GH insensitivity)”. Clin. Endocrinol. (Oxf). 65 (1): 114–7. doi:10.1111/j.1365-2265.2006.02558.x. PMID 16817829.
- ↑ Shevah O, Kornreich L, Galatzer A, Laron Z (2005). “The intellectual capacity of patients with Laron syndrome (LS) differs with various molecular defects of the growth hormone receptor gene. Correlation with CNS abnormalities”. Horm. Metab. Res. 37 (12): 757–60. doi:10.1055/s-2005-921097. PMID 16372230.
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