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Left ventricular aneurysm medical therapy

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Seyedmahdi Pahlavani, M.D. [2]

Overview

Afterload reduction and treatment of anginal pain, are the mainstay of medical therapy for small and medium-sized LV aneurysms.

Medical Therapy

Medical therapy is indicated for small and medium-sized LV aneurysms. The aim of medical therapy is to decrease cardiac work load (afterload reduction), provide anti ischemic therapy for chest pain, and anti coagulation if mural thrombosis exist.[1]

ACE inhibitors are the drug of choice for decreasing the afterload.
  • Anti ischemic therapy:
Many medications can be used to treat the underlying ischemic event, and also decrease the ischemic burden. Examples of such medications include:[1]
Nitrates | Beta Blockers | Calcium Channel Blockers | Potassium Channel Openers | Newer Anti-anginal Agents


References

  1. 1.0 1.1 Mann, Douglas (2015). Braunwald’s heart disease : a textbook of cardiovascular medicine. Philadelphia, PA: Elsevier/Saunders. ISBN 978-1455751341.


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