Lipoid pneumonia medical therapy

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ramyar Ghandriz MD [2]

Overview

Treatment of lipoid pneumonia is not well studied and published experience is only with case reports

Medical Therapy

Treatment of lipoid pneumonia is not well studied and published experience is only with some case reports.^[1]^[2]^[3]^[4]^[5]^[6]^[7]^[8]
In the case of exogenous lipoid pneumonia, avoiding ongoing exposure and providing supportive care is the mainstay of treatment.
As anti-inflammatory agents, corticosteroids are good option as a therapeutic option.
However, corticosteroids are not indicated in all cases and should be used with precautions if the lung injury is severe and ongoing.
Lipoid pneumonia being successfully treated with immunoglobulins and whole-lung lavage.
Repeated whole-lung lavage is especially useful in children.

References

↑ Spickard A, Hirschmann JV (1994). “Exogenous lipoid pneumonia”. Arch Intern Med. 154 (6): 686–92. PMID 8129503.
↑ Hadda, Vijay; Khilnani, Gopi C; Bhalla, Ashu S; Mathur, Sandeep (2009). “Lipoid pneumonia presenting as non resolving community acquired pneumonia: a case report”. Cases Journal. 2 (1): 9332. doi:10.1186/1757-1626-2-9332. ISSN 1757-1626.
↑ Beermann, B; Christensson, T; Moller, P; Stillstrom, A (1984). “Lipoid pneumonia: an occupational hazard of fire eaters”. BMJ. 289 (6460): 1728–1729. doi:10.1136/bmj.289.6460.1728. ISSN 0959-8138.
↑ Amato GM, Novara V, Amato G (1997). “[Lipid pneumonia. Favorable outcome after treatment with intravenous immunoglobulins, steroids, cephalosporins]”. Minerva Pediatr. 49 (4): 163–9. PMID 9244843.
↑ Chang, H Y; Chen, C W; Chen, C Y; Hsuie, T R; Chen, C R; Lei, W W; Wu, M H; Jin, Y T (1993). “Successful treatment of diffuse lipoid pneumonitis with whole lung lavage”. Thorax. 48 (9): 947–948. doi:10.1136/thx.48.9.947. ISSN 0040-6376.
↑ Marchiori, Edson; Zanetti, Gláucia; Mano, Claudia Mauro; Hochhegger, Bruno (2011). “Exogenous lipoid pneumonia. Clinical and radiological manifestations”. Respiratory Medicine. 105 (5): 659–666. doi:10.1016/j.rmed.2010.12.001. ISSN 0954-6111.
↑ Lin J, Huang LL, Zhang JW, Ye MH, Feng JX (2015). “Endogenous lipoid pneumonia presenting as solitary pulmonary nodule: a case report”. Int J Clin Exp Pathol. 8 (8): 9727–30. PMC 4583978. PMID 26464746.
↑ Sias, Selma M.A.; Daltro, Pedro A.; Marchiori, Edson; Ferreira, Angela S.; Caetano, Regina L.; Silva, Cleonice S.; Müller, Nestor L.; Moreira, Jose; Quirico-Santos, Thereza (2009). “Clinic and radiological improvement of lipoid pneumonia with multiple bronchoalveolar lavages”. Pediatric Pulmonology. 44 (4): 309–315. doi:10.1002/ppul.20918. ISSN 8755-6863.

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[pmid8129503-1] Spickard A, Hirschmann JV (1994). “Exogenous lipoid pneumonia”. Arch Intern Med. 154 (6): 686–92. PMID 8129503.

[HaddaKhilnani2009-2] Hadda, Vijay; Khilnani, Gopi C; Bhalla, Ashu S; Mathur, Sandeep (2009). “Lipoid pneumonia presenting as non resolving community acquired pneumonia: a case report”. Cases Journal. 2 (1): 9332. doi:10.1186/1757-1626-2-9332. ISSN 1757-1626.

[BeermannChristensson1984-3] Beermann, B; Christensson, T; Moller, P; Stillstrom, A (1984). “Lipoid pneumonia: an occupational hazard of fire eaters”. BMJ. 289 (6460): 1728–1729. doi:10.1136/bmj.289.6460.1728. ISSN 0959-8138.

[pmid9244843-4] Amato GM, Novara V, Amato G (1997). “[Lipid pneumonia. Favorable outcome after treatment with intravenous immunoglobulins, steroids, cephalosporins]”. Minerva Pediatr. 49 (4): 163–9. PMID 9244843.

[ChangChen1993-5] Chang, H Y; Chen, C W; Chen, C Y; Hsuie, T R; Chen, C R; Lei, W W; Wu, M H; Jin, Y T (1993). “Successful treatment of diffuse lipoid pneumonitis with whole lung lavage”. Thorax. 48 (9): 947–948. doi:10.1136/thx.48.9.947. ISSN 0040-6376.

[MarchioriZanetti2011-6] Marchiori, Edson; Zanetti, Gláucia; Mano, Claudia Mauro; Hochhegger, Bruno (2011). “Exogenous lipoid pneumonia. Clinical and radiological manifestations”. Respiratory Medicine. 105 (5): 659–666. doi:10.1016/j.rmed.2010.12.001. ISSN 0954-6111.

[pmid26464746-7] Lin J, Huang LL, Zhang JW, Ye MH, Feng JX (2015). “Endogenous lipoid pneumonia presenting as solitary pulmonary nodule: a case report”. Int J Clin Exp Pathol. 8 (8): 9727–30. PMC 4583978. PMID 26464746.

[SiasDaltro2009-8] Sias, Selma M.A.; Daltro, Pedro A.; Marchiori, Edson; Ferreira, Angela S.; Caetano, Regina L.; Silva, Cleonice S.; Müller, Nestor L.; Moreira, Jose; Quirico-Santos, Thereza (2009). “Clinic and radiological improvement of lipoid pneumonia with multiple bronchoalveolar lavages”. Pediatric Pulmonology. 44 (4): 309–315. doi:10.1002/ppul.20918. ISSN 8755-6863.

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